NSU Research Contributions
Title : Ascaris lumbricoids Infection as a Risk Factor for Asthma and Atopy in Rural Bangladeshi Children
Authors : Mohammad D. H. Hawlader, Enbo Ma, Emiko Noguchi, Makoto Itoh, Shams E. Arifeen, Lars Å. Persson, Sophie E. Moore, Rubhana Raqib, Yukiko Wagatsuma
| Journal Article Title: Tropical Medicine and Health | Volume Number: 42 | Publication Year : 2014 | Issue Number: 2 |
| Index: scopus | Ranking: Q2 | ISSN (Print): 1348-8945 | Publisher Name: Japanese Society of Tropical Medicine |
| Pages : 9 | |||
| ISSN (Online): 1349-4147 | |||
| Funding Source : None |
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Direct Sustainable Development Goals : SDG3 Good Health & Well-being |
Indirect Sustainable Development Goals : SDG4 Quality Education SDG10 Reduced Inequality |
Sustainable Development Sub Goals : Reduce premature mortality from non-communicable diseases and promote mental health and well-being Achieve universal health coverage Strengthen capacity for health risk management |
| Impact statement: This cross-sectional study of 912 children in rural Bangladesh addresses the ongoing controversy regarding whether helminth infections protect against or cause allergic diseases. The research identifies that repeated Ascaris infection—measured by high anti-Ascaris IgE levels—is a significant risk factor for ever-asthma, with those in the highest quartile being 1.86 times more likely to suffer from the condition. Crucially, the study establishes a powerful link between parasite exposure and atopy, finding that children with high anti-Ascaris IgE are nearly ten times more likely to be sensitive to house dust mites. These findings serve as a critical alert for healthcare providers in tropical environments, suggesting that chronic parasitic infections may actively drive the development of asthma and allergic sensitization in children. | Collaboration: Partner University | Keywords: Pediatric asthma, atopy, IgE, helminth infection, Bangladesh |
