Title : Ceftriaxone-induced hypersensitivity in pregnancy: Insights from a case of variable reactions to different brands


Authors : Mohammad Ashraful Amin, Sadia Monami, Tasnim Zerin Shama, Sabrina Nahin, and Mohammad Delwer Hossain Hawlader


Journal Article Title: Medical Reports Volume Number: 13 Publication Year : 2025
Index: indexed Ranking: No Ranking Publisher Name: Elsevier Ltd.
Pages : 3
ISSN (Online): 2949-9186
Funding Information:
Funding Source : None
Other Information:
Direct Sustainable Development Goals :
SDG3 Good Health & Well-being
Indirect Sustainable Development Goals :
SDG17 Partnership for the Goals
Sustainable Development Sub Goals :
Reduce maternal mortality
End preventable deaths of newborns and children under 5 years of age
Achieve universal health coverage
Impact statement: This case report documents a rare instance of brand-specific hypersensitivity to ceftriaxone in a pregnant patient, where one manufacturer's product caused a severe reaction while another was tolerated safely. By demonstrating that differences in formulation or excipients can influence drug tolerance, the research provides a critical mandate for individualized skin testing in obstetric care to ensure maternal and fetal safety when antibiotic options are limited by resistance Collaboration: None Keywords: Antibiotics, Pregnancy