NSU Research Contributions
Title : Inhibitory effects of vorinostat (SAHA) against food-borne pathogen Salmonella enterica serotype Kentucky mixed culture biofilm with virulence and quorum-sensing relative expression
Authors : Pantu Kumar Roy, Angela Ji-Won Ha, Shamsun Nahar, Md Iqbal Hossain, Md Ashrafudoulla, Sazzad Hossen Toushik, Md Furkanur Rahaman Mizan, Iksoon Kang, Sang-Do Ha
Abstract : Salmonella is a food-borne microorganism that is also a zoonotic bacterial hazard in the food sector. This study determined how well a mixed culture of Salmonella Kentucky formed biofilms on plastic (PLA), silicon rubber (SR), rubber gloves (RG), chicken skin and eggshell surfaces. In vitro interactions between the histone deacetylase inhibitor-vorinostat (SAHA)-and S. enterica serotype Kentucky were examined utilizing biofilms. The minimum inhibitory concentration (MIC) of SAHA was 120?µg mL?1. The addition of sub-MIC (60?µg mL?1) of SAHA decreased biofilm formation for 24?h on PLA, SR, RG, Chicken skin, and eggshell by 3.98, 3.84, 4.11, 2.86 and 3.01 log (p?
| Journal : Biofouling | Volume : 39 | Year : 2023 | Issue : 6 |
| Pages : 617-628 | City : | Edition : | Editors : |
| Publisher : | ISBN : | Book : | Chapter : |
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