NSU Research Contributions
Title : Comment on IgE responses to Ascaris and mite tropomyosins are risk factors for asthma
Authors : Haruko Takeuchi, Al Fazal Khan, Mohammad Imrul Hasan, Mohammad Delwer Hossain Hawlader, Mohammad Yunus, Khalequz Zaman, Hafizur R. Chowdhury, Sayaka Takanashi, Yukiko Wagatsuma, and Tsutomu Iwata
| Journal Article Title: Clinical & Experimental Allergy | Volume Number: 46 | Publication Year : 2015 | Issue Number: 1 |
| Index: scopus | Ranking: Q1 | ISSN (Print): 0954-7894 | Publisher Name: John Wiley & Sons Ltd. |
| Pages : 3 | |||
| ISSN (Online): 1365-2222 | |||
| Funding Source : None |
|
Direct Sustainable Development Goals : SDG3 Good Health & Well-being |
Indirect Sustainable Development Goals : SDG4 Quality Education SDG10 Reduced Inequality |
Sustainable Development Sub Goals : Reduce premature mortality from non-communicable diseases and promote mental health and well-being Achieve universal health coverage |
| Impact statement: This correspondence piece highlights the paradoxical relationship between declining helminthic infections and rising asthma prevalence in rural Bangladesh. The authors discuss how, despite a significant reduction in Ascaris infections following national deworming programs, asthma and wheezing rates have continued to climb, suggesting that anti-Ascaris IgE is a persistent risk factor for respiratory symptoms regardless of current infection levels. Crucially, the text emphasizes that co-exposure to both mites and Ascaris may exacerbate allergic symptoms, making it vital to study the immunological status of children in rapidly transitioning health landscapes. These insights serve as a call for continued research into how public health interventions like deworming interact with the development of allergic diseases in tropical regions. | Collaboration: Other | Keywords: Ascaris infection, asthma prevalence, wheezing, deworming, IgE, rural Bangladesh |
