NSU Research Contributions
Title : The Chameleon of rheumatology: A case of adult-onset Still’s disease
Authors : Mohammad Ashraful Amin, Ishtiakul Islam Khan, Ridwana Maher Manna, Sumyta Rahman, Nomaan Hassan Khan, Sabrina Nahin, and Mohammad Delwer Hossain Hawlader
| Journal Article Title: Medical Reports | Volume Number: 9 | Publication Year : 2025 |
| Index: indexed | Ranking: No Ranking | Publisher Name: Elsevier Ltd. |
| Pages : 5 | ||
| ISSN (Online): 2949-9186 | ||
| Funding Source : None |
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Direct Sustainable Development Goals : SDG3 Good Health & Well-being |
Indirect Sustainable Development Goals : SDG17 Partnership for the Goals |
Sustainable Development Sub Goals : Reduce premature mortality from non-communicable diseases and promote mental health and well-being Achieve universal health coverage |
| Impact statement: This case report details the diagnostic complexity of a 54-year-old male whose Adult-onset Still’s disease (AOSD) was initially mistaken for infectious diseases like tuberculosis or sarcoidosis. The patient’s rapid deterioration into hemophagocytic lymphohistiocytosis (HLH)—a severe "cytokine storm" with a predicted probability of over 99%- resulted in a fatal outcome despite aggressive treatment. By highlighting these diagnostic pitfalls, the study provides a critical mandate for early recognition and a multidisciplinary approach to managing rare autoimmune conditions that mimic sepsis in clinical settings. | Collaboration: None | Keywords: Adult-onset Still’s disease; Hemophagocytic lymphohistiocytosis; Macrophage activation syndrome |
