NSU Research Contributions
Title : HIV infection and multidrug resistant tuberculosis: a systematic review and meta-analysis
Authors : Zeeba Zahra Sultana, Farhana Ul Hoque, Joseph Beyene, Md. Akhlak-Ul-Islam, Md Hasinur Rahman Khan, Shakil Ahmed, Delwer Hossain Hawlader, and Ahmed Hossain
| Journal Article Title: BMC Infectious Diseases | Volume Number: 21 | Publication Year : 2021 |
| Index: scopus | Ranking: Q1 | Publisher Name: BMC |
| Pages : 13 | ||
| Funding Source : None |
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Direct Sustainable Development Goals : SDG3 Good Health & Well-being |
Indirect Sustainable Development Goals : SDG10 Reduced Inequality |
Sustainable Development Sub Goals : End the epidemics of AIDS, tuberculosis, malaria and neglected tropical diseases Ensure universal access to sexual and reproductive health-care services Achieve universal health coverage |
| Impact statement: This comprehensive systematic review and meta-analysis, encompassing 54 studies and over 430,000 patients, confirms that HIV-positive individuals are 1.42 times more likely to develop multidrug-resistant tuberculosis (MDR-TB) than those without HIV. The research highlights a particularly alarming risk in South-East Asia, where the odds are 1.86 times higher, and identifies that the risk increases significantly for patients aged 40 and older. Crucially, the study finds an even stronger association with primary MDR-TB (transmission-associated), indicating a growing upward trend in risk over the last decade. These findings serve as a critical call to action for global health authorities to prioritize enhanced diagnostic capabilities and equitable resource distribution to meet the WHO’s "End TB" targets by 2035. | Collaboration: Partner University | Keywords: Multidrug resistant, Drug-resistant, Tuberculosis, MDR-TB, HIV, Meta-analysis |
