Title : Vaccine approach for human monkeypox over the years and current recommendations to prevent the outbreak: a rapid review


Authors : Rifat Ara, Tajrin Rahman, Rima Nath, A.M.Khairul Islam, Miah MD Akiful Haque, Md. Ferdous Rahman, Mohammad Hayatun Nabi, and Mohammad Delwer Hossain Hawlader


Journal Article Title: F1000Research Volume Number: 11 Publication Year : 2022
Index: other (Crossref) Ranking: No Ranking Publisher Name: F1000 Research Ltd.
Pages : 18
ISSN (Online): 2046-1402
Funding Information:
Funding Source : None
Other Information:
Direct Sustainable Development Goals :
SDG3 Good Health & Well-being
Indirect Sustainable Development Goals :
SDG17 Partnership for the Goals
Sustainable Development Sub Goals :
End the epidemics of AIDS, tuberculosis, malaria and neglected tropical diseases
Achieve universal health coverage
Impact statement: This rapid review finds that although no specific monkeypox vaccine has been developed, the smallpox vaccine is up to 85% effective in preventing infection and provides long-term protection. The research highlights that third-generation vaccines (JYNNEOS/IMVAMUNE) are preferred over earlier generations due to significantly fewer side effects and are recommended for high-risk groups, including healthcare workers and laboratory professionals. By establishing that monkeypox is preventable through targeted vaccination in semi-endemic settings, the study provides a vital evidence-based mandate for governments to implement pre- and post-exposure prophylaxis while advocating for further human clinical trials to refine the safety and efficacy of current immunisation options. Collaboration: NGO Keywords: Monkeypox, Vaccine approach, Vaccine recommendations, Global health emergency