NSU Research Contributions
Title : Effective antimicrobial therapies of urinary tract infections among children in low- and middle-income countries: A systematic review
Authors : Rifat Ara, Sarker Mohammad Nasrullah, Zarrin Tasnim, Sadia Afrin, Mohammad Delwer Hossain Hawlader, and KM Saif-Ur-Rahman
| Journal Article Title: Pediatric Investigation | Volume Number: 7 | Publication Year : 2023 | Issue Number: 2 |
| Index: scopus | Ranking: Q3 | ISSN (Print): 2574-2272 | Publisher Name: John Wiley & Sons, Inc. |
| Pages : 9 | |||
| ISSN (Online): 2574-2272 | |||
| Funding Source : None |
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Direct Sustainable Development Goals : SDG3 Good Health & Well-being |
Indirect Sustainable Development Goals : SDG10 Reduced Inequality SDG17 Partnership for the Goals |
Sustainable Development Sub Goals : Reduce premature mortality from non-communicable diseases and promote mental health and well-being Achieve universal health coverage Enhance capacity-building support to developing countries for high-quality data and statistics |
| Impact statement: Urinary tract infections (UTIs) are a major cause of morbidity in children, yet treatment guidelines for developing countries are often lacking, and the rise of antibiotic resistance is rapidly limiting oral treatment options. This systematic review of six randomized controlled trials across 13 LMICs reveals that while newer drugs like cefadroxil show promise in preventing recurrence, there is a critical shortage of high-quality, large-scale clinical data specifically from these regions. By identifying that current treatments are often started empirically without local susceptibility data, the study provides a vital mandate for policymakers to invest in regional microbiological research and standardized clinical trials to protect children from long-term renal complications and the global threat of multidrug-resistant infections. | Collaboration: Partner University | Keywords: Children, Pediatrics, LMICs, Developing countries, Antibiotics, Antimicrobial therapies, Efficacy, Adverse events, Urinary trac |
